This is a preview. Log in through your library . Abstract The threading of more or less linear axle molecules through macrocyclic molecules, a fundamental process relating to the formation of ...

All biochemical reactions involve recognition, binding, and the formation of noncovalent complexes. Many small molecule drugs act by selectively binding to protein or nucleic acid targets and altering ...

image: A team of researchers from Kazan Federal University, Russia, led by Dr. Igor Sedov, reported an application of capillary differential scanning calorimetry technique for the study of the binding ...

Determining and evaluating the affinity of small molecule binding to a therapeutic target is a major component of drug discovery and lead optimization. In a technical note entitled “Label-free ...