A causative role for Notch signalling is well established in T cell acute lymphoblastic leukaemias (T-ALLs), which have activating mutations in the Notch genes resulting in a constitutively active ...

The notch in a wrench allows it to be used somewhat like a ratchet, as it lets the head stay on the fastener while you tighten or loosen.

The role of the Notch pathway during animal neural development is best understood in fruit flies, where Notch has been shown to inhibit differentiation by lateral signaling and regulate cell fate ...

Markus "Notch" Persson, the creator of Minecraft, made a rare appearance online on July 7, 2025, and stirred up a heated debate in the gaming world. After being quiet on social media for a while, ...

Notch signalling is involved in the cell-cell communication process via influencing the patterns of gene expression and differentiation. Notch pathway maintains stem cell populations and regulates ...

The notch signaling pathway plays a major role in regulating various cellular processes during development, therefore dysregulation of this pathway can lead to disease. This basic signaling pathway ...

** When you buy products through the links on our site, we may earn a commission that supports NRA's mission to protect, preserve and defend the Second Amendment. ** Q. At a gun show, I saw a Colt ...

Notch and the other founders of Mojang are selling their studio and Minecraft to Microsoft for $2.5 billion. In a blog post announcing the sale, Mojang's Owen Hill broke down the reasons for the sale, ...

Apple adds more screen real estate to the iPhone 13 with a redesigned camera system, but its notch may have a lot in common with this Pixel phone. Mike Sorrentino is a Senior Editor for Mobile, ...