p53 lies at the hub of a vast signalling network. Polymorphisms in upstream activators, repressors or downstream effectors of p53 might individually modulate cancer risk or interact with polymorphisms ...

Poly(ADP-ribose) (PAR) is synthesized from NAD + by PAR polymerases (PARPs) and regulates many physiological processes such as the maintenance of DNA integrity, gene expression and cell division.

Marketers assume that the more choices they offer, the more likely customers will be able to find just the right thing. They assume, for instance, that offering 50 styles of jeans instead of two ...

Colleen Murphy is a senior editor at Health. She has extensive experience with interviewing healthcare providers, deciphering medical research, and writing and editing health articles in an ...